Uburozi bukabije bwa enzyme ya fibrinolytike idafite amaraso ava muburozi bwa Agkistrodon

Ikintu gishya AA-MP-I cyatandukanijwe nuburozi bwa Agkistrodon acutus na chromatografiya ya thiophilique, Sephadex G-75, gel yubururu na POROS HQ 20 ion yo guhana chromatografiya.Enzyme ni poroteyine ya monomer ifite uburemere bwa 22.9 kDa, hamwe na isoelectric point ya 5.55, nta tsinda ryisukari ridafite aho ribogamiye, kandi N-terminal ikurikirana ni STEFQRYMEIVVDHSMVK.Ibisubizo byerekana ko ari PI metalloproteinase nshya, itumva ubushyuhe, ifite ibikorwa bya anticoagulant, igikorwa gikomeye cya anticagulant kuri 40 ℃, ifite uburozi bwa haemorhagie, kandi nta fosifolipase A: ibikorwa