Kwiga ku ngaruka zibuza polypeptide ntoya ya Agkistrodon acutus ubumara kuri selile A2780

Intego Gukora iperereza ku ngaruka zibuza agace gato ka polypeptide (K agace) kiva mu bumara bwa Agkistrodon acutus ku ikwirakwizwa ry’umurongo wa kanseri y’intanga ngabo A2780 hamwe nuburyo bukoreshwa.Uburyo MTT isuzuma ryakoreshejwe kugirango hamenyekane imikurire yikura rya K kumurongo wa kanseri;Ingaruka yo kurwanya selile yibigize K yagaragaye ikizamini cya adhesion;AO-EB inshuro ebyiri fluorescence irangi hamwe na cytometrike ikoreshwa kugirango hamenyekane ko apoptose ibaho.Ibisubizo K byabujije ikwirakwizwa ryingirabuzimafatizo ya kanseri yintanga ya A2780 mumibanire yigihe-ningaruka zifatika, kandi irashobora kurwanya ingirabuzimafatizo kuri FN.Apoptose yatahuwe na AO-EB inshuro ebyiri fluorescence yerekana kandi cytometrike.Umwanzuro Ibigize K bifite ingaruka zikomeye zo kubuza ikwirakwizwa rya kanseri yintanga ya kanseri yintanga ya A2780 muri vitro, kandi uburyo bwayo bushobora kuba bujyanye no kurwanya anti-selile no kwinjiza apoptose.