Ingaruka zirindwi za Antithrombotic Zakoreshejwe Ishusho Yihariye

Ingaruka ndwi za Antithrombotic zarakoreshejwe

Ibisobanuro bigufi:

Hariho ubwoko bubiri bwa poroteyine muburozi bwinzoka, bumwe murubwo bugororotse. Enzyme ishonga fibrin (protolysine) yitwa enzyme ya fibrin (protolysin) (Bigufi kuri plasminase, fi b ri no L yt I cenz YM E, FLE).Usibye gutesha agaciro fibrin na fibrinogen, Nta gukora plasminogene mumubiri wumuntu, nta hydrolysis yizindi mpamvu ziterwa na coagulation Na platelet membrane, ifite ingaruka za antithrombotic.Ibindi ni muburyo bwo guhagarikaProthrombin ikora kugirango itinde inzira ya coagulation kandi ntabwo ifite ibikorwa bya enzyme.

Ohereza imeri kuri twe

Ibicuruzwa birambuye

Ibicuruzwa

Iyi misemburo yakozwe bwa mbere na ATODA nibindi bivuye mubuyapani umuhondo-icyatsi cyicyuma umutwe winzoka
Uburyo bwa anticoagulant bwa proteine anticoagulant bwaganiriweho.
Ibi bigaragazwa no gukorana nibintu IX cyangwa kwambara X muri calcium ion
Ishirwaho rya 1: 1 bigoye kugirango ugere igihe kinini coagulation;Nyuma,
LU n'abandi.Agk I strodona CU
ACFI, ibintu birwanya anticoagulant, yitaruye ubumara bwinzoka.Liu Qing
Liang n'abandi.yize ibintu birwanya anticoagulant asanga AC FI irimo calcium ion
Kandi ibikorwa byayo birwanya anticagulant n'imiterere yabyo byari bifitanye isano na calcium ion.
Nyuma, Xu Xiaolong n'abandi.gutandukanya uburozi bwa agkistrodon halys muburyo bwiza bwo gutandukana
Ikindi kintu kirwanya anticoagulant, ACFI I, hamwe na anticoagulant yiyi anticagulant
Ubushakashatsi bwo gushyira mubikorwa uburyo, bwasanze busa na AC FI, nubwoko bwa kabiri.zhai
Ning n'abandi.yatandukanije ikintu gishya kirwanya ubumara bwa agkistrodon agkistrodon
Byagaragaye ko nta gikorwa cya fibrinolytike na fosifolipase A.
Igikorwa nigikorwa cyo kuva amaraso.Qian Xiaojiang n'abandi bo muri Hunan bakoze ingingo z'uburozi bwa agkistrodon
Ibikoresho bya Fibrinolytike byashyizwe mu bwigunge kandi byemejwe na trombolytic assay muri vitro
Ifite ingaruka zigaragara.Isuku yatandukanijwe nuburyo butatu bwa chromatografique
Kandi ibikorwa bya enzyme byatejwe imbere cyane.Kuberako ibice bya plasminase birimo
Ibice byo kuva amaraso biragoye gutandukana kandi agaciro kayo kavuriro ntigaragara.Li Zhaoyan nibindi
Binyuze mu mbaraga zo kubona enzyme ya fibrinolytique idafite amaraso, fibrinolytic enzyme ibisubizo byubuvuzi
Hamwe n'inkunga ya tekiniki.Zhou Xianli [18] yerekanye binyuze mubushakashatsi ko
Enzyme ya trombine na fibrinolytike yuburozi bwa agkistrodon halys bifite ingaruka zigaragara za trombolique, ariko
Ingaruka itaziguye ya enzyme ya fibrinolytique irakomeye kuruta trombine.
Trombin rero ni trombolytike gahoro gahoro, igenda ihindagurika yimiyoboro yamaraso,
Kongera kwihanganira imiyoboro y'amaraso mu gace ka ischemic, irinde guterwa amaraso biterwa no guturika kw'imitsi
Cleft, ifite ingaruka nziza kumurongo wambere wa trombose, byombi bikoreshwa